Chairperson: Albert C. Ludolph, Ulm, Germany
Vincenzo Silani, Milano, Italy
Diagnosis of amyotrophic lateral sclerosis (ALS) is considered difficult by many neurologists. However recent progress, in particular with regard to differential diagnosis, has made it a comparatively easy diagnosis which can be done in early stages. The knowledge of clinical phenotypes was refined during the past decades; MRI is a valuable aid in differential diagnosis, the same is true for clinical neurophysiology. Genetics contributes to the diagnosis, but also adds some ambiguities. Since the relation of ALS and frontotemporal dementias is now widely accepted, there is an increasing role of neuropsychology.
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