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Chairperson: Ralf Gold, Bochum, Germany

Epidemiological data speak for a marked increase in the incidence of multiple sclerosis (MS). Based on the recent update of the McDonald criteria, diagnosis of MS can already be made after the first relapse when magnetic resonance imaging gives evidence for dissemination in time. Yet at the same time the challenges for diagnosis have increased: there must be clear evidence that no other inflammatory or metabolic disease of the central nerves system mimics MS. In this course we will systematically discuss para-clinical methods which can further differentiate MS from other diseases. Examinations of cerebrospinal fluid, magnetic resonance imaging, but also electrophysiological methods are the mainstay for further corroborating the diagnosis of MS. Finally clinical vignettes will be presented.

Neurophysiological assessment of MS

Letizia Leocani

Milan, Italy

Imaging in MS - typical features

Frederik Barkhof

Amsterdam, The Netherlands

CSF biomarkers in MS

Manuel Comabella

Barcelona, Spain

MS and clinical differential diagnosis

Ralf Gold

Bochum, Germany

Self enrolment (Student)