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Chairperson: Stefano F. Cappa, Milan, Italy “Typical” Alzheimer’s disease (AD) is defined clinically by an onset characterised by progressive episodic memory dysfunction, reflecting pathological involvement of medial temporal lobe structures. It is now widely recognized that different clinical presentations may actually be associated with the pathological hallmarks of AD. These include progressive disorders of language, fulfilling the criteria for primary progressive aphasia, progressive visuo-spatial dysfunction (described as the posterior cortical atrophy syndrome), and progressive disorders of executive function and behavior (possibly reflecting prominent prefrontal involvement). Familiarity with these “atypical” phenotypes is crucial in cognitive neurology, not only because they are diagnostically challenging, but also because they may provide important insights into AD pathogenesis. |
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| Posterior cortical atrophy |
Philip Scheltens Amsterdam, The Netherlands |
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| Logopenic aphasia |
Stefano F. Cappa Milan, Italy |
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| Frontal Alzheimer’s disease |
Florence Pasquier Lille, France |
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| Biomarkers for atypical Alzheimer’s disease |
Martin N. Rossor London, United Kingdom |
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